Medtech Portfolio Optimization: Why Investors Say No

In the medtech world, a “no” from an investor isn’t always what it seems. The decision to pass on a startup often comes down to more than just the technology—it’s a balancing act of risk, timing, and fit. And for the investors themselves, building a smart portfolio means getting comfortable with saying no—a lot.

The Risk-Reward Dance

The heart of the conversation revolved around a common challenge: how do medtech investors decide when a startup is worth the risk?

Diana shared her experience passing on SIA during its Series A round. Despite FDA 510(k) clearance and a ready-to-launch product, she flagged a lack of clinical data and market validation. “It was all unknown,” she said. “Even though the product was approved, the addressable market size was unclear. That was perceived as a big risk.”

Visit here: https://www.yumpu.com/en/document/view/70881036/medtech-portfolio-optimization-why-investors-say-no




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